Here is the detailed overview of Capreomycin Powder for Injection 1 g, with icons:
๐ Capreomycin Powder for Injection 1 g
๐งช Nature / Drug Class
๐น Antibiotic
๐น Second-line anti-tuberculosis agent
๐น Belongs to cyclic polypeptide class
๐น Bacteriostatic action (inhibits bacterial protein synthesis)
๐ฉบ Purpose / Indications
โ Used in the treatment of:
- ๐ฆ Multidrug-resistant tuberculosis (MDR-TB)
- ๐ In combination with other anti-TB medications
- ๐ Reserved for resistant or refractory TB cases
โ๏ธ Advantages
โ๏ธ Effective against resistant strains of Mycobacterium tuberculosis
โ๏ธ Useful when first-line TB drugs (like isoniazid, rifampicin) fail
โ๏ธ Intramuscular or IV administration ensures systemic availability
โ๏ธ Prolonged dosing possible in DOTS-Plus programs
๐ฆ Common Packaging
๐ฆ Glass vials with 1 g sterile powder
๐ง Requires reconstitution with sterile water before injection
๐ For IM or slow IV use
โ ๏ธ Patient Advice / Precautions
๐ Administer once daily (typically)
๐ฆป Monitor for ototoxicity (hearing loss, tinnitus)
๐งช Regularly monitor:
- Renal function (creatinine)
- Electrolytes (potassium, magnesium)
- Hearing tests (audiometry)
๐ซ Do not mix with other injectables in the same syringe
๐ง Maintain hydration to reduce nephrotoxicity risk
๐ซ Contraindications / Cautions
โ Known allergy to capreomycin or similar agents
โ ๏ธ Use cautiously in:
- Renal impairment
- Elderly patients
- Concurrent use of other nephrotoxic/ototoxic drugs (e.g., aminoglycosides)
๐ง Storage
๐ก๏ธ Store the unreconstituted vial at 15โ25ยฐC (room temp)
๐ง Once reconstituted, use immediately or refrigerate and use within 24 hours
๐งด Protect from light and moisture