Here is the detailed pharmaceutical profile for:
💉 Calcium Gluconate Injection 100 mg/mL
✅ DESCRIPTION
Calcium gluconate is an injectable form of calcium used to correct acute and severe hypocalcemia. Each mL contains 100 mg of calcium gluconate, which provides about 9.3 mg of elemental calcium.
⚖️ COMPOSITION
- Each mL contains:
- Calcium gluconate 100 mg
- Equivalent to approx. 9.3 mg elemental calcium
- In a sterile aqueous solution for intravenous (IV) or slow intramuscular (IM) use (IV preferred)
🌿 NATURE
- Mineral salt
- Water-soluble calcium compound
- Less irritating to veins than calcium chloride
📌 USES
- Acute symptomatic hypocalcemia
- Cardiac arrest due to hyperkalemia
- Calcium channel blocker overdose
- Magnesium sulfate toxicity (e.g., in eclampsia)
- Neonatal hypocalcemia
- As a calcium supplement in ICU settings
🌟 ADVANTAGES
- Safer than calcium chloride for IV administration
- Effective emergency treatment for life-threatening low calcium
- Less irritating to blood vessels
- Useful in electrolyte correction in critical care
⚠️ PRECAUTIONS
- Monitor ECG during IV administration
- Administer slowly to prevent cardiac arrhythmias
- Do not mix with phosphates or sulfates in the same IV line
- Caution in:
- Renal insufficiency
- Digitalis (digoxin) therapy
- Hypercalcemia risk
❌ CONTRAINDICATIONS
- Hypercalcemia
- Ventricular fibrillation
- Digitalis toxicity
- Hypersensitivity to calcium salts
💢 SIDE EFFECTS
- Local irritation, thrombophlebitis
- Hypotension, bradycardia if infused too rapidly
- Tingling, flushing, metallic taste
- Tissue necrosis if extravasation occurs
💊 DOSAGE & ADMINISTRATION
- IV infusion (preferred route)
- Usually 10 mL of 10% solution (i.e., 1 gram calcium gluconate)
- Administer slowly over 5–10 minutes with ECG monitoring
- May be diluted in 50–100 mL of 5% dextrose or 0.9% saline for slow infusion
📦 PACKING
- Typically supplied in:
- 10 mL ampoules (10% w/v = 100 mg/mL)
- 20 mL vials in some setups
🧊 STORAGE
- Store at controlled room temperature (15–25°C)
- Do not freeze
- Protect from light and contamination