💊 Medicine Name:
Bortezomib
💉 Formulation:
Lyophilized Powder for Injection
💪 Strength:
2 mg per vial
📜 Description:
Bortezomib is a proteasome inhibitor used as an anticancer agent. It interferes with protein degradation in cancer cells, leading to apoptosis. It’s primarily used in the treatment of multiple myeloma and mantle cell lymphoma.
🧾 Prescription:
Rx Only — Administered by a trained healthcare provider, usually in a hospital or oncology clinic.
📦 Common Packaging:
- Single-use glass vial containing 2 mg of lyophilized powder
- Requires reconstitution before use
- Labeled as a cytotoxic agent — handle with gloves and caution
🧊 Storage:
- Unopened vials: Store at 2–8°C (refrigerator), protect from light
- Reconstituted solution: Use within 8 hours when stored at room temperature (do not refrigerate)
⚠️ Precautions:
- Peripheral neuropathy: Common and dose-limiting; may require dose adjustment
- Thrombocytopenia and neutropenia: Monitor CBC
- Hepatotoxicity: Liver enzymes should be monitored
- Herpes zoster reactivation: Consider antiviral prophylaxis
- Hypotension, GI symptoms, tumor lysis syndrome
👨⚕️ Patient Advice:
- Report numbness, tingling, or muscle weakness
- Maintain hydration and nutrition
- Avoid driving if feeling dizzy or weak
- Do not take vaccines without doctor’s approval
- Antiviral prophylaxis may be needed (to prevent shingles)