💊 Medicine Name:
Bleomycin
💉 Formulation:
Powder for Injection (Lyophilized)
💪 Strength:
15 units per vial
(Equivalent to 15 IU of bleomycin activity)
📜 Description:
Bleomycin is a cytotoxic glycopeptide antibiotic derived from Streptomyces verticillus. It is used as an antineoplastic agent, primarily in combination chemotherapy regimens.
🧾 Prescription:
Prescription-only medicine (Rx)
To be administered under the supervision of oncology specialists.
📦 Common Packaging:
- 15 units lyophilized powder in a single-use glass vial
- Requires reconstitution before administration
- Labeled: Cytotoxic – Handle with care
🧊 Storage:
- Store vials at 2–8°C (refrigerated)
- Protect from light
- Reconstituted solution: Use immediately or store as per manufacturer’s guidance
⚠️ Precautions:
- Pulmonary toxicity is the most serious adverse effect (may be fatal)
- Monitor for cough, dyspnea, pulmonary infiltrates
- Use caution in:
- Renal impairment (dose adjustment may be needed)
- Elderly patients
- Test dose may be given before first full dose due to hypersensitivity risk
- No radiation therapy to lungs during treatment → risk of enhanced toxicity
👨⚕️ Patient Advice:
- Report shortness of breath, persistent cough, or chest pain immediately
- Stay well hydrated and follow dosing schedule
- Avoid smoking or oxygen therapy, which may increase lung toxicity
- Use effective contraception during and after therapy
- Routine lung function tests (PFTs) may be advised