Here is the detailed overview of Bendamustine Hydrochloride Injection 100 mg/vial with icons:
💉 Bendamustine Hydrochloride Injection 100 mg/vial
🧪 Nature / Drug Class
🔹 Anticancer (Chemotherapy) Agent
🔹 Alkylating agent with purine analog properties
🔹 Causes DNA cross-linking, leading to cell cycle arrest and tumor cell death
🩺 Purpose / Indications
✅ Used in the treatment of:
- 🧬 Chronic Lymphocytic Leukemia (CLL)
- 🦠 Indolent Non-Hodgkin’s Lymphoma (iNHL)
- 🔁 Off-label: Multiple myeloma, Mantle cell lymphoma, Hodgkin’s lymphoma (under oncologist supervision)
⚙️ Advantages
✔️ Effective in first-line and relapsed settings
✔️ Can be combined with rituximab or other agents
✔️ Suitable for patients not responding to other therapies
✔️ Short infusion time compared to some other regimens
📦 Common Packaging
📦 Vial contains 100 mg of Bendamustine hydrochloride
💉 Supplied as lyophilized powder for IV reconstitution
🧪 Also available in 25 mg vials for flexible dosing
⚠️ Patient Advice / Precautions
🧪 Reconstitute with Sterile Water for Injection
💧 Dilute in 0.9% Sodium Chloride (Normal Saline)
⏱️ IV infusion over 30–60 minutes, usually on Day 1 & Day 2 of 28-day cycles
📋 Monitor closely for:
- 🩸 Myelosuppression (neutropenia, anemia, thrombocytopenia)
- 🧫 Infections, tumor lysis syndrome
- 🧪 Liver & kidney function
🚫 Not for intrathecal administration
🚼 Contraindicated in pregnancy and breastfeeding
🧊 Storage
🌡️ Store vial at 2–8°C (Refrigerated)
💉 After reconstitution: Use immediately or as per manufacturer’s stability guidelines
🧒 Keep away from children