💊 Baclofen Tablet 20 mg
📘 Description:
Baclofen 20 mg is a centrally acting skeletal muscle relaxant primarily used to treat spasticity resulting from multiple sclerosis, spinal cord injuries, and other neurological disorders. It reduces excessive muscle tone and involuntary spasms by acting on the central nervous system (CNS).
🔬 Formulation:
- Active Ingredient: Baclofen
- Strength: 20 mg per tablet
- Dosage Form: Oral tablet
- Common Brands: Lioresal®, Bacloflex®, Bacfen®, Kemstro®
- Route: Oral administration
🧪 Nature / Mechanism of Action:
- Drug Class: GABA-B receptor agonist
- Mechanism: Acts on gamma-aminobutyric acid (GABA) receptors in the spinal cord, inhibiting nerve signal transmission that causes muscle spasms and rigidity.
🩺 Indications / Uses:
- ✅ Management of muscle spasticity due to:
- Multiple sclerosis (MS)
- Spinal cord injury or disease
- Cerebral palsy (in some cases)
- Stroke (occasionally used)
- ✅ Off-label:
- Alcohol dependence/cravings
- Chronic hiccups
- Certain types of neuropathic pain
✅ Advantages:
- Higher strength for moderate to severe spasticity
- Reduces painful spasms, clonus, and rigidity
- Improves movement and function in patients with neurological conditions
- Can be combined with physical therapy for optimal outcomes
- Available in multiple oral strengths for easy titration
⚠️ Precautions:
- Use with caution in:
- Elderly patients (higher risk of sedation, falls)
- Renal impairment (accumulation may occur)
- Patients with psychiatric history or epilepsy
- Do not stop suddenly — may cause withdrawal symptoms:
- Hallucinations
- Delirium
- Seizures
- Rebound spasticity
📦 Storage:
- Store below 30°C (room temperature)
- Protect from moisture and light
- Keep out of reach of children