💊 Baclofen Tablet 10 mg
📘 Description:
Baclofen 10 mg tablet is a centrally acting muscle relaxant and antispastic agent. It is commonly prescribed to relieve muscle spasticity caused by neurological conditions such as multiple sclerosis, spinal cord injuries, and cerebral palsy. It works by modulating nerve signals in the central nervous system.
🔬 Formulation:
- Active Ingredient: Baclofen
- Strength: 10 mg per tablet
- Dosage Form: Oral tablet (round, usually white)
- Common Brands: Lioresal®, Bacloflex®, Bacfen®, etc.
- Route of Administration: Oral (by mouth)
🧪 Nature / Mechanism of Action:
- Drug Class: GABA (gamma-aminobutyric acid) analog
- Mechanism: Baclofen acts primarily on GABA-B receptors in the spinal cord, inhibiting the release of excitatory neurotransmitters and decreasing muscle hyperactivity and spasms.
🩺 Indications / Uses:
- ✅ Relief of skeletal muscle spasticity due to:
- Multiple sclerosis
- Spinal cord injury or disease
- Cerebral palsy
- ✅ Off-label uses:
- Chronic hiccups
- Alcohol use disorder (to reduce cravings)
- Neuropathic pain and trigeminal neuralgia (in select cases)
✅ Advantages:
- Reduces muscle stiffness, pain, and spasms
- Improves mobility and quality of life
- Can be titrated gradually to find the lowest effective dose
- Available in multiple strengths and dosage forms
- Orally active and generally well tolerated
⚠️ Precautions:
- Use with caution in elderly and in patients with renal impairment
- May cause CNS depression (drowsiness, sedation, dizziness)
- Do not stop abruptly – can result in withdrawal symptoms: hallucinations, rebound spasticity, seizures
- Avoid alcohol and other CNS depressants while using baclofen
- Monitor for mental health side effects (e.g., depression, confusion)
📦 Storage:
- Store at 15–30°C (room temperature)
- Keep in a dry, dark place, tightly closed
- Keep out of reach of children