β 1. Formulations Covered
Strength Range: 300 mg to 500 mg
Types of Tablets:
- Effervescent Tablets
- Dispersible Tablets
- Enteric-Coated Tablets
These formulations differ in absorption rate, gastrointestinal tolerance, and intended use.
β 2. Common Uses (Indications)
- Pain relief (headache, muscle ache, toothache, menstrual cramps)
- Fever reduction
- Anti-inflammatory uses (e.g., arthritis, rheumatic conditions)
- Mild to moderate pain and fever in cold and flu
- Sometimes for antiplatelet therapy in special cases (though usually lower doses are used)
β 3. Formulation Differences
πΉ Effervescent Tablets
- Dissolve completely in water before consumption
- Rapid absorption β fast onset of action
- Gentle on the stomach due to buffered formulation
- Suitable for those with swallowing difficulty
- Example Brands: Disprin CV 500, Aspirin Effervescent 500
πΉ Dispersible Tablets
- Disperse in a small amount of water before use
- Work faster than regular tablets
- Often used in fever or pain management
- Less irritating than plain tablets
- Common in adult and pediatric doses
πΉ Enteric-Coated Tablets
- Have a protective coating to resist stomach acid
- Dissolve in the intestine, not the stomach
- Slower onset but less gastric irritation
- Used when long-term treatment is required (e.g., in heart disease)
- Do not crush or chew
- Example Brands: Ecosprin 325, Aspirin EC 300
β 4. Common Packaging
- Strengths: 300 mg, 325 mg, 500 mg
- Pack Sizes: Blister packs of 10, 12, or 15 tablets
- Bottle packs (less common)
- May be generic or branded
β 5. Storage Instructions
- Store below 25Β°C
- Keep in dry place, away from moisture
- Protect effervescent tablets from humidity (keep in foil or tube)
- Keep out of reach of children
β 6. Patient Advice
- Effervescent/Dispersible:
- Dissolve in water fully before drinking
- Do not swallow whole
- Enteric-Coated:
- Swallow whole with water
- Take after food to protect the stomach
- Do not crush or chew
- Avoid using with other NSAIDs or alcohol
- Not recommended for:
- Children under 16 (due to risk of Reyeβs syndrome)
- Patients with ulcers, bleeding disorders, or aspirin-sensitive asthma
- Inform doctor if:
- You are pregnant, breastfeeding, or on blood thinners