Here is a complete overview of Acetazolamide 250 mg Tablets:
✅ DESCRIPTION
Acetazolamide is a carbonic anhydrase inhibitor used primarily to treat glaucoma, altitude sickness, and certain types of seizures and edema. It helps reduce fluid accumulation and intraocular pressure.
🧪 FORMULATION
- Active Ingredient: Acetazolamide 250 mg per tablet
- Excipients:
- Lactose
- Corn starch
- Magnesium stearate
- Microcrystalline cellulose
- Sodium starch glycolate
(may vary by manufacturer)
- Dosage Form: Oral tablet
- Appearance: Usually round or oblong white tablets
🌿 NATURE
- Type: Sulfonamide derivative
- Class: Carbonic anhydrase inhibitor (diuretic and antiglaucoma agent)
- Action: Inhibits carbonic anhydrase enzyme → reduces hydrogen ion secretion → promotes diuresis and decreases production of aqueous humor in the eye.
💊 USES
- Glaucoma: Reduces intraocular pressure
- Acute Mountain Sickness (AMS): Helps prevent/treat symptoms of altitude sickness
- Epilepsy: Adjunct treatment in certain types of seizures
- Edema: Used in fluid retention associated with heart failure or drug-induced swelling
- Periodic Paralysis: In some genetic conditions
- Idiopathic intracranial hypertension (off-label)
🌟 ADVANTAGES
- Effective in rapidly lowering intraocular pressure
- Useful prophylaxis for altitude sickness
- Adjunct therapy for drug-resistant seizures
- Can be used orally and in injectable forms
- Helps avoid surgical options in some glaucoma cases
⚠️ PRECAUTIONS
- Allergy warning: Avoid if allergic to sulfonamides
- Use with caution in:
- Kidney or liver impairment
- Diabetes
- Electrolyte imbalance
- Pregnancy (Category C – consult doctor)
- May cause:
- Tingling in fingers/toes
- Drowsiness, fatigue
- Nausea, vomiting
- Electrolyte disturbances (e.g., hypokalemia)
- Regular monitoring of blood counts and electrolytes is advised
- Avoid alcohol
- Can interact with diuretics, lithium, aspirin, anticonvulsants
🧊 STORAGE
- Store at room temperature (15°C to 30°C)
- Keep in a dry place away from moisture and light
- Keep out of reach of children
- Do not use expired tablets