Chloroquine Tablet 150 mg

💊 Chloroquine Tablet 150 mg

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📌 Description:

1. Chloroquine 150 mg tablet contains chloroquine phosphate, equivalent to approximately 90 mg of base.
2. It is a synthetic antimalarial and anti-inflammatory agent.
3. The tablet is usually film-coated, white or light-colored, and scored for splitting.
4. Used for prophylaxis and treatment of malaria caused by sensitive Plasmodium strains.
5. Also applied in autoimmune disorders, including rheumatoid arthritis and lupus.

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🧪 Nature:

1. Belongs to the 4-aminoquinoline class of drugs.
2. Exhibits blood schizonticidal activity, acting on the erythrocytic forms of malaria parasites.
3. Has anti-inflammatory and lysosomotropic properties.
4. Well absorbed orally, with a large volume of distribution and long half-life.
5. Primarily metabolized in the liver and excreted via the kidneys.

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💡 Advantages:

1. Cost-effective treatment option in areas with chloroquine-sensitive malaria.
2. Long half-life allows weekly dosing for prophylaxis.
3. Effective in both treatment and prevention of malaria.
4. Also used in rheumatologic disorders, reducing steroid dependency.
5. Widely available and on the WHO Essential Medicines list.

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💊 Uses:

1. Treatment of acute malaria due to Plasmodium vivax, P. ovale, P. malariae, and sensitive P. falciparum.
2. Prophylaxis of malaria in regions with low resistance.
3. Used in the management of systemic lupus erythematosus (SLE).
4. Treatment of rheumatoid arthritis as a disease-modifying agent.
5. Occasionally used in hepatic amebiasis, in combination with other agents.

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🏥 Storage:

1. Store in a cool, dry place below 25°C.
2. Protect from light and moisture.
3. Keep in the original blister pack or container to maintain stability.
4. Keep out of reach of children, as overdose can be highly toxic or fatal.
5. Avoid use past expiry; discard unused tablets according to local regulations.

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