Chloroquine Oral liquid 50 mg/5 mL

💊 Chloroquine Oral Liquid 50 mg/5 mL

---

📌 Description:

1. Chloroquine Oral Liquid contains 50 mg of chloroquine phosphate per 5 mL.
2. It is a synthetic antimalarial agent with additional anti-inflammatory properties.
3. Specially formulated for pediatric use or patients with swallowing difficulties.
4. Appears as a clear to slightly colored syrup, often flavored for palatability.
5. Used primarily in prophylaxis and treatment of malaria, especially Plasmodium vivax.

---

🧪 Nature:

1. 4-aminoquinoline compound acting on the asexual blood stages of malaria parasites.
2. Rapidly absorbed from the GI tract, with good systemic availability.
3. Accumulates in parasite’s food vacuole and inhibits heme polymerase.
4. Also exhibits anti-inflammatory effects, useful in some autoimmune disorders.
5. Has a long half-life, supporting weekly dosing for prophylaxis.

---

💡 Advantages:

1. Effective and cost-efficient antimalarial treatment in sensitive regions.
2. Oral liquid format allows accurate dosing in children.
3. Useful in treating extraintestinal amebiasis and certain autoimmune diseases.
4. Generally well tolerated when dosed correctly.
5. Long history of use makes it clinically familiar and accessible in many settings.

---

💊 Uses:

1. Treatment of acute attacks of malaria caused by P. vivax, P. ovale, and P. malariae.
2. Prophylaxis of malaria in endemic regions.
3. Management of hepatic amebiasis (in combination with other agents).
4. Occasionally used in lupus erythematosus and rheumatoid arthritis.
5. Off-label use in porphyria cutanea tarda and sarcoidosis.

---

🏥 Storage:

1. Store at room temperature (15–25°C) away from heat and direct light.
2. Keep the bottle tightly closed to prevent contamination or evaporation.
3. Do not freeze. Shake well before each use.
4. Ensure accurate measuring device is used (oral syringe or cup).
5. Keep out of reach of children to avoid accidental overdose, which can be fatal.

---