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💊 Clindamycin Capsule 300 mg
📌 Description:
- Clindamycin Capsule 300 mg is a broad-spectrum lincosamide antibiotic.
- Each capsule contains 300 mg of clindamycin hydrochloride, equivalent to clindamycin base.
- It is used for serious bacterial infections caused by susceptible anaerobic or Gram-positive bacteria.
- The capsule is usually hard gelatin, available in blister or strip packs.
- It is a prescription-only medication, often used when penicillins are contraindicated.
🧪 Nature:
- Bacteriostatic or bactericidal depending on the concentration and organism.
- Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
- Active against anaerobes, Staphylococcus, Streptococcus, and Pneumococci.
- Exhibits excellent tissue penetration, including into bone and abscesses.
- Does not cross the blood-brain barrier, so not suitable for CNS infections.
💡 Advantages:
- Effective against anaerobic infections, especially abdominal or pelvic sepsis.
- Used in penicillin-allergic patients as an alternative antibiotic.
- Provides rapid absorption and reliable systemic action via oral route.
- Penetrates well into bone and joint tissues, useful in osteomyelitis.
- Suitable for multi-drug therapy in serious polymicrobial infections.
💊 Uses:
- Treatment of respiratory tract infections, including pneumonia and sinusitis.
- Used in skin and soft tissue infections such as cellulitis and abscesses.
- Management of pelvic inflammatory disease (PID) and intra-abdominal infections.
- Part of combination therapy for malaria (with quinine) in some guidelines.
- Used in dental infections and for prophylaxis in dental surgery in high-risk patients.
🏥 Storage:
- Store at room temperature below 25°C.
- Keep away from light, moisture, and direct heat.
- Ensure capsules are kept in original container until use.
- Do not freeze or expose to high humidity environments.
- Keep out of reach of children and pets, and dispose of expired medication properly.
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