Primaquine Tablet 2.5 mg

💊 Primaquine Tablet 2.5 mg

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📌 Description:

1. Primaquine Tablet 2.5 mg is a low-dose antimalarial medication used mainly in pediatric or G6PD-sensitive individuals.
2. Contains 2.5 mg of primaquine phosphate, suitable for precise weight-based dosing.
3. Used for radical cure of malaria and prevention of relapse, especially in P. vivax and P. ovale infections.
4. The tablet is generally small-sized and uncoated, allowing easy dosing adjustments.
5. Available in specialized malaria treatment programs and pediatric formulations.

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🧪 Nature:

1. Member of the 8-aminoquinoline antimalarial class.
2. Exhibits schizonticidal and gametocytocidal action, targeting liver and sexual forms of malaria parasites.
3. Primarily metabolized in the liver, forming active compounds.
4. Acts by interfering with mitochondrial function in parasites.
5. Has a narrow therapeutic index, especially in G6PD-deficient individuals.

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💡 Advantages:

1. Low-dose formulation allows safe and accurate treatment for infants or low body weight patients.
2. Prevents relapse of P. vivax and P. ovale malaria, reducing disease burden.
3. Aids in malaria transmission control through gametocyte elimination.
4. Allows tailored regimens, especially in settings with G6PD testing protocols.
5. May be used in fractionated dosing schemes for better tolerance.

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💊 Uses:

1. Radical cure of relapsing malaria in pediatric patients.
2. Blocking transmission of P. falciparum by targeting gametocytes.
3. Used in weight-adjusted dosing regimens in young children.
4. Administered as part of malaria elimination campaigns in endemic areas.
5. Sometimes used under research settings for pediatric antiprotozoal therapies.

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🏥 Storage:

1. Store below 25°C, away from excess heat and direct sunlight.
2. Keep in original packaging to protect from moisture and contamination.
3. Do not expose tablets to high humidity or freezing temperatures.
4. Ensure child-safe storage, especially in areas with pediatric use.
5. Dispose of unused or expired tablets per local pharmaceutical guidelines.