Quinine Tablet 300 mg

๐Ÿ“Œ Description:

  1. Quinine is an alkaloid compound obtained from the bark of the Cinchona tree.
  2. It is commonly used in tablet form for the treatment of malaria caused by Plasmodium falciparum.
  3. Each tablet contains 300 mg of quinine sulfate or quinine hydrochloride, depending on the formulation.
  4. It works by disrupting the parasite’s ability to break down and metabolize hemoglobin inside red blood cells.
  5. Quinine tablets are usually white, film-coated, and bitter-tasting.

๐Ÿงช Nature:

  1. Belongs to the class of cinchona alkaloids and antimalarial agents.
  2. Available in solid oral dosage form; often tablets or capsules.
  3. Exhibits a bitter taste, characteristic of natural quinoline derivatives.
  4. Has antimalarial, analgesic, and antipyretic properties.
  5. It is partially water-soluble and undergoes hepatic metabolism.

๐Ÿ’ก Advantages:

  1. Convenient oral route of administration for uncomplicated malaria.
  2. Effective against chloroquine-resistant P. falciparum malaria.
  3. Useful in combination therapy with doxycycline, clindamycin, or tetracycline.
  4. Available in many malaria-endemic countries at an affordable price.
  5. Can be used in pregnancy (Category C) when no safer alternatives are available.

๐Ÿ’Š Uses:

  1. Treatment of uncomplicated malaria due to P. falciparum.
  2. Used as part of combination regimens to prevent resistance.
  3. Occasionally used for nocturnal leg cramps (though not commonly recommended now).
  4. Treatment of relapse or resistant malaria cases.
  5. Sometimes used as a second-line antimalarial agent in certain countries.

๐Ÿฅ Storage:

  1. Store at controlled room temperature, between 15โ€“25ยฐC (59โ€“77ยฐF).
  2. Keep in a dry place, away from moisture and humidity.
  3. Protect from light exposure and direct sunlight.
  4. Store in original packaging to prevent contamination or degradation.
  5. Keep out of reach of children and only dispense with a valid prescription.

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