Quinine Injection 300 mg/mL

📌 Description:

1. Quinine is a natural alkaloid derived from the bark of the Cinchona tree.
2. It is used as an antimalarial drug, particularly for severe Plasmodium falciparum infections.
3. The injection contains 300 mg of quinine salt (commonly quinine dihydrochloride or gluconate) per mL.
4. It acts by interfering with the parasite’s ability to digest hemoglobin in red blood cells.
5. The preparation is usually for intravenous (IV) use in hospital settings.

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🧪 Nature:

1. Quinine is classified as a cinchona alkaloid and antimalarial agent.
2. It is available as a sterile aqueous solution, usually clear to slightly yellow.
3. The injectable form is water-soluble and often comes in ampoules or vials.
4. The drug exhibits bitter taste and light sensitivity.
5. It has anti-parasitic, antipyretic, and mild analgesic properties.

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💡 Advantages:

1. Effective in treating severe or complicated malaria, especially in resistant strains.
2. Rapid onset of action when given parenterally.
3. Life-saving in cerebral malaria and multi-organ involvement.
4. Available in settings where newer antimalarials (like artesunate) may not be.
5. Often included in national malaria control programs in endemic regions.

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💊 Uses:

1. Treatment of severe Plasmodium falciparum malaria (especially IV route).
2. May be used as part of combination therapy with antibiotics like doxycycline or clindamycin.
3. Occasionally used for Babesiosis in rare cases.
4. Emergency antimalarial in settings lacking access to artesunate.
5. Used in hospital ICU settings for critical care malaria management.

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🏥 Storage:

1. Store at 25°C (77°F); excursions permitted to 15–30°C.
2. Protect from light and freezing.
3. Keep ampoules or vials in the original outer packaging until use.
4. Should be stored in a secure, sterile location.
5. Check for any precipitation or discoloration before administration.

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