Here is the detailed drug profile for:
💉 Cefuroxime Powder for Injection 1500 mg
📘 Description:
Cefuroxime 1500 mg injection (usually as Cefuroxime sodium) is a second-generation cephalosporin antibiotic administered parenterally (IV or IM) to treat moderate to severe infections caused by susceptible bacteria.
💊 Prescription / Indications:
Used in the treatment of:
- Lower respiratory tract infections (e.g. pneumonia)
- Urinary tract infections (UTI)
- Skin and soft tissue infections
- Bone and joint infections
- Septicemia
- Meningitis
- Surgical prophylaxis
🌿 Nature / Drug Class:
- Cephalosporin antibiotic – 2nd generation
- Bactericidal (kills bacteria)
- Broad-spectrum: active against Gram-positive and Gram-negative organisms
✅ Advantages:
- Effective against β-lactamase–producing bacteria
- Stable in the presence of many common resistance mechanisms
- Widely used in hospitals
- Dual route of administration: IV or IM
- Reliable for perioperative infection prevention
⚠️ Precautions:
- Allergy risk: Avoid in patients with known cephalosporin or severe penicillin allergy
- Renal dose adjustment may be necessary
- Use with caution in neonates and elderly patients
- Do not mix with aminoglycosides in the same syringe/solution
- May alter prothrombin time in prolonged use
📦 Common Packaging:
- Glass vial with 1500 mg lyophilized powder
- Supplied as dry powder for reconstitution
- For IV or IM injection (reconstitute with appropriate diluent: sterile water or saline)
❄️ Storage:
- Before reconstitution:
- Store in a cool, dry place (below 25°C)
- Protect from light and moisture
- After reconstitution:
- Use immediately or within 6–24 hours if refrigerated (depends on diluent)
- Do not freeze reconstituted solution
- Follow hospital/label-specific stability guidelines