Here is the detailed overview for:
💧 Cloxacillin Oral Liquid 125 mg/5 mL (p)
(p = Paediatric formulation)
📘 Description:
Cloxacillin Oral Liquid is a penicillinase-resistant antibiotic suspension, mainly used in children and infants to treat infections caused by β-lactamase-producing staphylococci. Each 5 mL contains 125 mg of cloxacillin.
💊 Prescription / Indications:
Prescribed for the treatment of bacterial infections including:
- Skin and soft tissue infections (impetigo, boils)
- Otitis media (ear infection)
- Pharyngitis and tonsillitis
- Lower respiratory tract infections (pneumonia, bronchitis)
- Bone and joint infections (e.g., osteomyelitis)
- Infections after minor wounds or surgery
🩺 Uses:
- Especially for paediatric patients who can’t swallow capsules
- Targets penicillinase-producing staphylococci
- Used as an oral follow-up to injectable antibiotics in children
- Suitable for mild to moderate bacterial infections
🌿 Nature:
- Drug Class: Penicillin antibiotic (β-lactam, penicillinase-resistant)
- Form: Reconstitutable oral suspension
- Route: Oral
- Type: Prescription-only (Rx)
- Mechanism: Inhibits bacterial cell wall synthesis → bactericidal
✅ Advantages:
- Effective against Staph. aureus (non-MRSA)
- Convenient oral formulation for children
- Can be used in home-based therapy
- Generally well tolerated
- Available as a palatable flavored syrup for better compliance
⚠️ Precautions:
- Contraindicated in children allergic to penicillin or cephalosporins
- Administer on an empty stomach (1 hour before or 2 hours after meals)
- Shake well before each use
- Common side effects:
- Mild GI upset (nausea, diarrhea)
- Skin rash, hypersensitivity
- Rare: liver enzyme changes, eosinophilia
- Use with caution in children with liver or kidney disorders
- Complete the full course to avoid resistance
📦 Common Packaging:
- Supplied as a dry powder in a bottle, to be reconstituted with sterile water
- Bottle label usually indicates:
- 125 mg cloxacillin per 5 mL after reconstitution
- Pack sizes: 30 mL, 60 mL, or 100 mL bottles
❄️ Storage:
- Before reconstitution: Store in a cool, dry place below 25°C
- After reconstitution:
- Store in a refrigerator (2–8°C)
- Use within 7 to 14 days (check label)
- Do not freeze
- Keep out of reach of children