Here is the detailed overview for:
💊 Cefixime Tablet 400 mg
🧪 Nature / Drug Class
- Third-generation cephalosporin antibiotic
- Broad-spectrum bactericidal agent
- Effective against gram-positive and gram-negative organisms
🩺 Purpose / Indications
Used in treatment of:
- Acute otitis media
- Pharyngitis and tonsillitis
- Uncomplicated urinary tract infections (UTIs)
- Lower respiratory tract infections (e.g., bronchitis)
- Typhoid fever
- Uncomplicated gonorrhea
- Sinusitis
⚙️ Advantages
✔️ Once-daily dosing improves compliance
✔️ Useful in typhoid and resistant UTI infections
✔️ Stable against many β-lactamase producing organisms
✔️ Often well-tolerated
✔️ Convenient oral alternative to injectable cephalosporins
💊 Dosage & Administration
- Adults and adolescents (≥12 years):
‣ 400 mg once daily or 200 mg twice daily - Typhoid: 400 mg once daily for 7–14 days
- Uncomplicated gonorrhea: Single dose of 400 mg
- Take with or without food
- Adjust dose in renal impairment
📦 Common Packaging
- Strip of 1, 3, or 10 tablets
- Each film-coated tablet contains Cefixime 400 mg
⚠️ Patient Advice / Precautions
- Complete the full prescribed course
- May cause mild GI upset – take with food if needed
- Caution in penicillin-allergic patients
- Report persistent diarrhea, as it may signal Clostridioides difficile
- Not first-line in hospital-acquired or serious systemic infections
💢 Common Side Effects
- Nausea, abdominal pain, diarrhea
- Rash, hypersensitivity reactions
- Rare: Liver enzyme elevation, hematologic abnormalities
🧊 Storage
- Store below 25°C, away from moisture
- Keep in original blister pack until use