Formulation: A sterile, clear, colorless to pale yellow solution containing enoxaparin sodium, a low molecular weight heparin (LMWH), typically supplied in a pre-filled syringe.
Concentration: Each 0.6 mL syringe delivers 60 milligrams (mg) of enoxaparin, specifically designed for subcutaneous injection.
Advantages
Potent Anticoagulation: Provides strong efficacy in preventing and treating various thromboembolic disorders, including DVT and PE.
Convenient Administration: The pre-filled syringe facilitates easy and often self-administered subcutaneous injections, enhancing patient convenience.
Uses
Treatment of DVT/PE: Commonly used for the active treatment of established Deep Vein Thrombosis (DVT) with or without Pulmonary Embolism (PE).
ACS Management: Indicated in the management of Acute Coronary Syndromes (ACS), including Unstable Angina (UA), Non-ST-elevation Myocardial Infarction (NSTEMI), and ST-elevation Myocardial Infarction (STEMI).
Nature
Low Molecular Weight Heparin (LMWH): Enoxaparin is a depolymerized derivative of unfractionated heparin, characterized by its smaller and more uniform molecular size.
Mechanism of Action: Primarily exerts its anticoagulant effect by enhancing the activity of antithrombin III, leading to a predominant inhibition of activated Factor Xa in the coagulation cascade.
Storage
Temperature: Store at controlled room temperature, typically between 20∘C to 25∘C (68∘F to 77∘F).
Protection & Disposal: Keep the pre-filled syringe in its original carton to protect from light; do not freeze; designed for single-dose use, and any unused portion must be discarded.
