Here is the complete overview for:
💉 Amoxicillin Powder for Injection 1000 mg (1 g)
🧪 Nature / Drug Class
🔹 Beta-lactam antibiotic
🔹 Belongs to the aminopenicillin group
🔹 Bactericidal: Inhibits bacterial cell wall synthesis
🔹 Often used alone or in combination with beta-lactamase inhibitors
🩺 Purpose / Indications
Used to treat a wide range of moderate to severe bacterial infections, including:
- Respiratory tract infections (e.g., pneumonia, bronchitis)
- Urinary tract infections
- Skin and soft tissue infections
- Intra-abdominal infections
- Bone and joint infections
- Septicemia
- Endocarditis (with other antibiotics)
- Surgical prophylaxis
⚙️ Advantages
✔️ Rapid effect via IV or IM injection
✔️ Useful when oral administration is not feasible
✔️ Effective against gram-positive and gram-negative bacteria
✔️ May be used in pediatric and adult populations under proper supervision
💉 Dosage & Administration
- Route: Intramuscular (IM) or Intravenous (IV)
- Reconstitution:
- Typically with sterile water for injection
- Reconstitute 1 g vial with ~10 mL sterile water for IV use
- Administer slow IV injection or infuse over 30 minutes
- Dosage varies based on infection severity, age, renal function
📦 Common Packaging
- Glass vial containing 1 g (1000 mg) of sterile amoxicillin sodium
- Single-use vial for IM/IV administration
- May also be available in combo form with clavulanic acid
⚠️ Patient Advice / Precautions
- Inform physician of penicillin or cephalosporin allergy
- Report any skin rash, breathing difficulty, or swelling
- Kidney function monitoring advised for prolonged use or in elderly
- Use with caution in patients with history of seizures
- Avoid mixing with other drugs in same syringe or infusion line
💢 Common Side Effects
- Local: Injection site pain, swelling, or redness
- Systemic:
- Rash, urticaria
- Diarrhea, nausea
- Rare: Hypersensitivity, anaphylaxis, Clostridioides difficile infection
🧊 Storage
- Store vial below 25°C, protect from heat and moisture
- Once reconstituted:
- Use immediately
- Do not freeze
- Discard any unused solution