Here is the detailed overview for:
💉 Pegylated Interferon Alfa-2a Injection 120 mcg
🧪 Nature / Drug Class
🔹 Pegylated long-acting interferon
🔹 Cytokine and immunomodulator
🔹 Acts as both antiviral and immune enhancer
🔹 Pegylation provides sustained activity and weekly dosing
🩺 Purpose / Indications
✅ Used in treatment of:
- Chronic Hepatitis B
- Chronic Hepatitis C (especially genotype-specific)
✅ Reduces viral replication and inflammation
✅ Sometimes used in oncology or blood disorders (off-label)
⚙️ Advantages
✔️ Once-weekly injection — improved compliance
✔️ Longer half-life than standard interferons
✔️ Can slow fibrosis progression in liver disease
✔️ Option for patients not responding to oral antivirals
📦 Common Packaging
📦 Supplied as prefilled syringe or single-use vial
💉 Given by subcutaneous injection once per week
📄 Includes usage instructions and safety guide
⚠️ Patient Advice / Precautions
🧪 Routine monitoring:
- CBC, Liver function tests, Thyroid function
- Mental health evaluation (depression/anxiety risk)
💧 Encourage hydration and rest post-injection
🔁 Rotate injection sites to reduce irritation
🛑 Avoid alcohol and drugs harmful to liver
👩⚕️ Treatment should be supervised by a specialist
🚫 Contraindications / Cautions
❌ History of severe psychiatric illness (e.g. suicidal ideation)
❌ Autoimmune hepatitis or severe liver disease (non-viral)
⚠️ Caution in:
- Cardiac conditions
- Uncontrolled diabetes or seizures
🚫 Not for use during pregnancy or breastfeeding
🧊 Storage
🧊 Refrigerate at 2°C to 8°C
🚫 Do not freeze
☀️ Protect from light
📦 Keep in original container until ready to use