Here is the full overview for:
๐ Lamivudine + Nevirapine + Stavudine Tablet
Each tablet contains:
- Lamivudine (A) โ 150 mg
- Nevirapine (B) โ 200 mg
- Stavudine (C) โ 30 mg
๐งช Nature / Drug Class
๐น Fixed-Dose Combination Antiretroviral (ARV)
๐น Drug classes:
- Lamivudine & Stavudine: NRTIs (Nucleoside Reverse Transcriptase Inhibitors)
- Nevirapine: NNRTI (Non-Nucleoside Reverse Transcriptase Inhibitor)
๐ฉบ Purpose / Indications
โ
Treatment of HIV-1 infection in adults and adolescents
โ
Part of first-line ART in earlier national programs
โ
Reduces viral load and increases CD4 count
โ
Often used in resource-limited settings due to cost-effectiveness
โ๏ธ Advantages
โ๏ธ Triple-drug combination โ simplifies treatment
โ๏ธ Enhances patient adherence
โ๏ธ Offers effective viral suppression
โ๏ธ Available as once or twice daily dosing depending on protocol
๐ฆ Common Packaging
๐ฆ Usually available in blister strips or plastic bottles
๐งด Solid oral tablet form, taken with or without food
๐ Typical dose: 1 tablet twice daily (verify with current guidelines)
โ ๏ธ Patient Advice / Precautions
๐งช Regular liver function monitoring โ Nevirapine may cause hepatotoxicity
๐ฆถ Monitor for peripheral neuropathy (Stavudine)
๐ฉธ Check for anemia/neutropenia (Lamivudine side effects)
๐ Rash and hypersensitivity may occur (especially in early weeks)
๐ Maintain strict adherence to avoid resistance
๐ญ Avoid alcohol and hepatotoxic drugs
๐ซ Contraindications / Cautions
โ Allergy to any active ingredient
โ ๏ธ Use caution in:
- Liver impairment
- History of pancreatitis or peripheral neuropathy
- Pregnancy (due to Stavudine risks)
๐ง Storage
๐ก๏ธ Store below 25ยฐC
๐ Protect from moisture and light
๐ Keep out of reach of children