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✅ 1. Description / Prescription
- Generic Name: Sodium Valproate
- Formulation: Oral Liquid / Syrup
- Strength: 200 mg per 5 mL
- Route: Oral
- Prescription Required: ✔️ Yes
- Indications:
- Management of epilepsy (all types of seizures)
- Mood stabilization in bipolar disorder (off-label in children or adults unable to swallow tablets)
- Sometimes used for migraine prophylaxis
✅ 2. Nature of the Medicine
- Class: Anticonvulsant / Antiepileptic
- Type: Pediatric and adult-use liquid formulation
- Mechanism of Action:
- Increases GABA levels in the brain (inhibitory neurotransmitter)
- Stabilizes overactive neurons and suppresses seizure activity
- Also modulates sodium and calcium channels to regulate nerve transmission
✅ 3. Advantages
- Easier to swallow, especially for:
- Children
- Elderly
- Patients with swallowing difficulties
- Allows precise dosing adjustment (e.g., by body weight in children)
- Faster onset of action than tablets in some cases
- Can be dosed multiple times daily or adjusted easily
✅ 4. Common Packaging
- Bottle Size: Usually 100 mL or 200 mL
- Concentration: 200 mg per 5 mL
- Measuring Device: Supplied with a measuring cup or oral syringe
- Labeling Note: May be written as:
- “Sodium Valproate Oral Solution 200 mg/5 mL”
- Or “Valproic Acid equivalent” (based on the brand)
✅ 5. Storage Conditions
- Store below 25°C
- Do not freeze
- Shake well before use
- Keep tightly closed and out of reach of children
- Use within 30–60 days after opening (check label)
✅ 6. Patient Advice
- Take with food or milk to reduce stomach irritation
- Use the measuring device provided — do not use a kitchen spoon
- Shake the bottle well before each dose
- Maintain regular dosing times each day
- Do not stop the medication abruptly without medical advice
- Avoid alcohol and sedative medications unless approved
- Inform your doctor if:
- You feel unusually tired, confused, or unwell
- You notice signs of liver or pancreas problems (e.g., abdominal pain, vomiting, jaundice)
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