Here is the detailed overview of Leuprolide Acetate Powder for Injection 22.5 mg with icons:
💉 Leuprolide Acetate Powder for Injection 22.5 mg
🧪 Nature / Drug Class
🔹 Gonadotropin-Releasing Hormone (GnRH) Agonist
🔹 Long-acting synthetic hormone analog
🔹 Suppresses production of testosterone or estrogen
🩺 Purpose / Indications
✅ Used in:
- 👨 Advanced Prostate Cancer (palliative treatment)
- 👩 Endometriosis
- 🩸 Uterine Fibroids
- 👧 Central Precocious Puberty (CPP)
- 📋 Off-label: certain hormone-responsive cancers & IVF protocols
⚙️ Advantages
✔️ 3-month depot formulation (extended release)
✔️ Reduces frequency of injections compared to monthly dosing
✔️ Strong suppression of gonadotropins, lowering sex hormone levels
✔️ Convenient for long-term hormone therapy
📦 Common Packaging
📦 Vial with 22.5 mg lyophilized powder
💧 Includes sterile diluent for reconstitution
💉 Administered as a single intramuscular (IM) injection every 3 months
⚠️ Patient Advice / Precautions
🕒 Schedule: once every 12 weeks (3 months)
📈 Initial hormone flare may worsen symptoms temporarily
🧪 Monitoring required:
- Hormone levels, PSA, or estradiol
- Bone density (especially in long-term use)
- Renal & liver function, blood glucose in older patients
❗ Possible side effects: - 🔥 Hot flashes, mood swings, headache
- ↓ Sexual function, libido, possible depression
- 🦴 Risk of bone loss over time
🚫 Not for use in pregnancy
🧊 Storage
🌡️ Store between 2–8°C (refrigerated)
🧴 Reconstitute immediately before injection
🧒 Keep out of reach of children