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✅ 1. Description / Prescription
- Generic Name: Sodium Valproate
- Dosage Form: Oral Tablet
- Strength: 500 mg
- Route of Administration: Oral
- Prescription Required: ✔️ Yes
- Indications:
- Treatment of epilepsy (all types of seizures)
- Mood stabilization in bipolar disorder
- Prevention of migraines
✅ 2. Nature of the Medicine
- Drug Class: Antiepileptic / Anticonvulsant / Mood stabilizer
- Mechanism of Action:
- Enhances GABA (inhibitory neurotransmitter) activity in the brain
- Modulates sodium and calcium channels to stabilize neuronal activity
- Suppresses abnormal electrical signals in the brain
✅ 3. Advantages
- Broad-spectrum seizure control (works for multiple seizure types)
- Also effective in managing manic episodes in bipolar disorder
- Used for long-term treatment with once or twice daily dosing
- Available in controlled-release (CR) or enteric-coated forms to reduce gastric irritation
✅ 4. Common Packaging
- Tablet Form: Film-coated or enteric-coated
- Type: Immediate Release (IR) or Controlled Release (CR)
- Pack Size: Blister strip of 10 or 15 tablets, or bottle packaging
- Marking: Often labeled as “Sodium Valproate 500 mg” or with brand names like Epilim, Valparin, etc.
✅ 5. Storage Conditions
- Store Below: 25°C (77°F)
- Protect from: Moisture and direct sunlight
- Container: Keep in original blister or airtight container
✅ 6. Patient Advice
- Take with food to reduce nausea or gastric irritation
- Swallow whole – do not crush or chew, especially if enteric-coated or CR
- Maintain consistent timing every day (e.g., morning and evening)
- Do not stop abruptly without doctor’s guidance — may trigger seizures
- Avoid alcohol, sedatives, and other CNS depressants
- Inform your doctor if you experience:
- Mood changes
- Jaundice or abdominal pain
- Tremors or drowsiness
- Women of childbearing age:
- Strictly avoid in pregnancy unless no alternative exists
- Use effective contraception and consult doctor before pregnancy
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