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✅ 1. Description / Prescription
- Generic Name: Sodium Valproate
- Dosage Form: Oral Tablet
- Strength: 300 mg
- Route: Oral
- Prescription Required: ✔️ Yes
- Indications:
- Epilepsy: Generalized, partial, and other seizure types
- Bipolar Disorder: As a mood stabilizer
- Migraine Prophylaxis
✅ 2. Nature of the Medicine
- Therapeutic Class: Anticonvulsant / Mood Stabilizer
- Mechanism of Action: Increases GABA (gamma-aminobutyric acid) levels in the brain — an inhibitory neurotransmitter that calms abnormal nerve activity.
- May also affect sodium and calcium channels to stabilize electrical activity in the brain.
✅ 3. Advantages
- Broad-spectrum efficacy against different types of seizures
- Also effective for bipolar mood swings and migraine prevention
- Once or twice-daily dosing with extended-release forms
- May be used as monotherapy or adjunct therapy
✅ 4. Common Packaging
- Form: Film-coated or enteric-coated tablets
- Packaging: Blister packs or HDPE bottles
- Typical Pack Size: 10, 15, or 30 tablets per strip
- Labeling Note: Sometimes labeled with “Valproic Acid equivalent”
✅ 5. Storage Conditions
- Temperature: Store below 25°C (77°F)
- Humidity: Protect from moisture
- Light: Keep away from direct sunlight
- Packaging: Keep in original packaging until use
✅ 6. Patient Advice
- Take with food to reduce gastric upset
- Swallow whole — do not chew or crush if not dispersible
- Take at the same time every day
- Do not stop abruptly — could trigger seizures
- Avoid alcohol and sedatives
- Regular monitoring: Liver function tests, CBC, and valproate levels may be required
- In Women:
- Can cause serious birth defects — avoid during pregnancy unless absolutely necessary
- Use effective contraception and consult your doctor before planning pregnancy
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