💊 Clobazam Tablet 5 mg
📌 1. Prescription / Indication:
Clobazam 5 mg tablets are used in the treatment of:
- Epilepsy: as adjunct therapy in seizures (especially Lennox-Gastaut syndrome, partial and generalized seizures)
- Anxiety disorders (short-term use only)
- Sometimes used in acute agitation or muscle spasms (off-label)
📄 2. Description:
- Dosage form: Oral tablet
- Strength: 5 mg Clobazam per tablet
- Route: Oral
- Appearance: Usually white or off-white, round tablets
- Prescription: Required (Schedule H drug in India; controlled substance in some countries)
🔬 3. Nature / Pharmacological Class:
- Class: Benzodiazepine derivative
- Mechanism: Enhances the effect of GABA (gamma-aminobutyric acid) at the GABA-A receptor → calming, anticonvulsant effect
- Long-acting benzodiazepine with less sedation than diazepam
🌟 4. Advantages:
- Effective as an add-on therapy in refractory epilepsy
- Has both anxiolytic and anticonvulsant effects
- Less sedating compared to other benzodiazepines
- Long half-life allows once or twice daily dosing
- Useful in pediatric and adult epilepsy management
📦 5. Common Packaging:
| Package Size | Form |
|---|---|
| 10 tablets | Blister strip |
| 30 tablets | Blister strip or bottle |
🧊 6. Storage Guidelines:
- Store below 25°C in a dry place
- Protect from light and moisture
- Keep out of reach of children
- Do not use after expiry date
👩⚕️ 7. Patient Advice:
- Take exactly as prescribed—do not exceed dose
- Take with or after food to reduce stomach upset
- Do not stop suddenly—risk of withdrawal seizures
- May cause:
- Drowsiness
- Dizziness
- Fatigue
- Avoid alcohol and operating machinery
- Inform your doctor if:
- You are pregnant/planning pregnancy
- You have liver or kidney disease
- You notice mood changes or suicidal thoughts
- Not meant for long-term anxiety use (risk of dependence)
🎯 8. Purpose / Medical Uses:
- Seizure control in epilepsy (especially Lennox-Gastaut syndrome)
- Adjunctive therapy with other anticonvulsants
- Short-term management of severe anxiety (rare, limited duration)
⚠️ 9. Warnings / Precautions:
- Not for long-term monotherapy in anxiety
- Avoid in myasthenia gravis, severe respiratory insufficiency
- Risk of dependence, tolerance, and withdrawal
- Use with caution in elderly (falls, confusion)