Glycerin/glycerol (as mentioned in IP) Topical

💧 Glycerin / Glycerol (Topical) – As per Indian Pharmacopoeia (IP)


🔹 1. Prescription / Indication:

Glycerin (also called Glycerol) is an over-the-counter (OTC) topical agent used for:

  • Moisturizing dry, rough, or scaly skin
  • Soothing irritated or inflamed skin
  • Relieving minor burns, cuts, and abrasions
  • Softening hardened skin (e.g. corns, calluses)
  • Part of emollient formulations or medicated creams/lotions

🔹 2. Description:

  • Form: Clear, colorless, viscous liquid
  • Taste: Sweet
  • Odor: Odorless
  • Nature: Hydrophilic, hygroscopic (attracts moisture from air)
  • IP Grade: Glycerin conforms to Indian Pharmacopoeia specifications

🔹 3. Composition (IP Grade):

IngredientConcentrationRemarks
Glycerol98%–101% w/wAs per IP standards, minimum 98% purity

🔹 4. Advantages:

  • Excellent skin hydrator (humectant)
  • Non-irritating, safe for all skin types, including babies
  • Used in dermatology, cosmetics, oral care, and wound healing
  • Compatible with most creams, ointments, and solutions

🔹 5. Nature / Drug Class:

  • Type: Topical emollient and humectant
  • Class: Moisturizer / Protectant
  • Mechanism: Draws water into the outer skin layer to keep skin soft and supple

🔹 6. Common Packaging:

  • Plastic or glass bottles – 100 mL, 200 mL, 500 mL
  • Often labeled as:
    • Glycerin IP” or “Glycerol IP
    • For external use only
  • May be packed with dropper, especially in pediatric formulations

🔹 7. Storage:

  • Store in a cool, dry place
  • Keep tightly closed to avoid contamination
  • Protect from moisture and direct sunlight
  • Shelf life: 2–3 years depending on packaging

🔹 8. Patient Advice / How to Use:

  • Apply directly to clean, dry skin or affected area
  • Use 1–3 times daily or as directed by doctor/pharmacist
  • Can be diluted with water before use for sensitive skin
  • For oral ulcers (if indicated), can be applied with a cotton swab
  • Avoid contact with eyes or mucous membranes unless prescribed

🔹 9. Purpose / Clinical Use:

UsesHow it helps
Dry skin / cracked heelsSoftens and hydrates
Minor wounds / burnsProtects skin, promotes healing
Diaper rashSoothes and forms barrier
Oral ulcer / mouth drynessCoats and relieves irritation
Corns and calluses (with salicylic acid)Aids in softening hardened skin

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