🧴 Framycetin Cream 1%
🔹 1. Prescription / Indication:
Framycetin 1% cream is a topical antibiotic used for the treatment and prevention of bacterial skin infections, including:
- Infected wounds and cuts
- Minor burns
- Skin ulcers
- Infected dermatitis/eczema
- Post-surgical wound infections
- Superficial bacterial skin infections (e.g. impetigo)
🔹 2. Description:
- Form: Topical cream
- Strength: 1% w/w Framycetin sulfate (equivalent to ~10 mg/g)
- Color: White or off-white smooth cream
- Application: Apply thinly 2–3 times daily
- Route: External use only
🔹 3. Advantages:
- Broad-spectrum bactericidal activity against:
- Staphylococcus
- Streptococcus
- Escherichia coli
- Proteus, Klebsiella, etc.
- Promotes faster wound healing
- Topical use minimizes systemic absorption
- Well-tolerated on intact and broken skin
🔹 4. Nature / Pharmacological Class:
- Class: Topical aminoglycoside antibiotic
- Mechanism:
- Inhibits protein synthesis in bacterial cells by binding to the 30S ribosomal subunit
- Leads to bacterial cell death (bactericidal)
🔹 5. Common Packaging:
- Aluminum tubes or plastic tubes
- Available in 5 g, 10 g, 15 g, 30 g, 50 g tubes
- Outer carton box with leaflet
🔹 6. Storage:
- Store at below 25°C (77°F)
- Keep away from heat, moisture, and direct light
- Do not freeze
- Keep tube tightly closed
- Keep out of reach of children
🔹 7. Patient Advice / Counseling:
- Clean and dry affected area before applying
- Apply thin layer gently on the affected area
- Avoid contact with eyes, mouth, nose, and inner ears
- Do not apply over large areas or deep wounds without medical supervision
- Wash hands after use
- Avoid long-term use to reduce risk of antibiotic resistance or skin sensitization
- Discontinue if rash, itching, or irritation develops
- Not recommended for fungal or viral infections
🔹 8. Purpose / Clinical Use:
- To treat and prevent minor skin infections
- Commonly used in:
- First aid kits
- Post-operative care
- Dermatitis with secondary infection
- Can be used with dressing or bandage