Lamivudine Tablet 150 mg

Here is the full information for Lamivudine Tablet 150 mg:


💊 Lamivudine Tablet 150 mg


🧪 Generic Name:

Lamivudine

📦 Dosage Form & Strength:

  • Tablet – 150 mg

🌐 Therapeutic Class:

  • Nucleoside Reverse Transcriptase Inhibitor (NRTI)
  • Primarily used for HIV treatment, in combination with other antiretrovirals

Indications / Uses:

  • HIV-1 infection (in combination with other antiretroviral agents)
  • May be used in dual or triple-drug ART regimens

⚖️ Usual Adult Dosage:

  • 150 mg twice daily
    or
  • 300 mg once daily (if using extended regimens or fixed-dose combinations)

Note: Lamivudine 150 mg is not typically used alone—always as part of combination therapy for HIV.


⚠️ Precautions:

  • Monitor for lactic acidosis, hepatomegaly with steatosis
  • Monitor renal function – dose adjustment needed if CrCl <50 mL/min
  • Avoid monotherapy to prevent HIV resistance

🚫 Contraindications:

  • Known hypersensitivity to lamivudine
  • Should not be used as monotherapy in HIV patients

💥 Common Side Effects:

  • Nausea, fatigue, headache
  • Cough, abdominal pain
  • Neutropenia (less common)
  • Rare: Lactic acidosis, pancreatitis, liver dysfunction

🤝 Drug Combinations:

Often used with:

  • Zidovudine
  • Tenofovir
  • Efavirenz or Dolutegravir

📦 Packaging & Storage:

  • Tablets in blister packs or HDPE bottles
  • Store below 30°C, away from light and moisture

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