Here is the detailed non-branded medicine profile for:
💧 Glucose Injection 25% (Dextrose 25%)
✅ DESCRIPTION
Glucose Injection 25% is a sterile, hypertonic intravenous solution containing 25 g of glucose per 100 mL of water for injection. It is used for rapid correction of severe hypoglycemia and as a concentrated calorie source when fluid restriction is needed.
🧪 FORMULATION
- Concentration: 25% w/v (25 g glucose per 100 mL)
- Form: Solution for injection
- Route: Intravenous (IV)
- Common volumes: 20 mL, 50 mL, 100 mL (mostly in ampoules or vials)
🌿 NATURE
- Highly hypertonic solution (osmolarity ~1380 mOsm/L)
- Caloric value: ~850 kcal/L
- Sterile, non-pyrogenic
- Does not contain preservatives
📌 USES
- Severe hypoglycemia, especially in unconscious patients
- Parenteral nutrition when fluid intake must be restricted
- As a caloric supplement in combination with other IV solutions
- Sometimes used in emergency pediatric resuscitation protocols
🌟 ADVANTAGES
- Rapid glucose availability
- Useful in fluid-restricted patients
- Small volume, high-calorie delivery
- Can be used as an adjunct in treating hyperkalemia (with insulin)
⚠️ PRECAUTIONS
- Strict IV use only—never give subcutaneously or intramuscularly
- Monitor blood glucose, electrolytes, and fluid status regularly
- Avoid extravasation (can cause tissue necrosis)
- Use cautiously in patients with diabetes, renal impairment, or cardiac failure
❌ CONTRAINDICATIONS
- Hyperglycemia, diabetes (uncontrolled)
- Delirium tremens (if patient is dehydrated)
- Intracranial bleeding
- Anuria or fluid overload states
- Known allergy to glucose
💢 SIDE EFFECTS
- Hyperglycemia
- Local irritation, phlebitis
- Electrolyte disturbances (especially dilutional effects)
- Fluid overload
- Tissue damage if extravasation occurs
📥 PACKING
- Usually supplied in ampoules, vials, or small volume bottles
- Common pack sizes: 20 mL, 50 mL, 100 mL
🧊 STORAGE
- Store at 15–25°C
- Protect from light
- Use immediately after opening
- Discard if cloudy or contains particles