Glucose Injection 25 %

🔹 Glucose Injection 25% – As Licensed


📄 Description:

Glucose Injection 25% is a hypertonic sterile solution of D-glucose in water, used for rapid correction of hypoglycemia and as a source of calories in patients unable to eat or absorb glucose orally. It is for intravenous use only.


💊 Prescription / Use:

  • Indications:
    • Severe hypoglycemia
    • As a caloric supplement in patients with poor oral intake
    • As part of parenteral nutrition
    • Drug diluent in IV preparations
    • Management of insulin overdose
  • Dosage:
    • Must be administered intravenously only
    • Dosage depends on clinical condition, age, weight, and glucose levels
    • Typical adult emergency dose: 25–50 mL (6.25–12.5 g of glucose)
  • Route: Intravenous (IV) only
  • Administration: Given slowly under medical supervision

🔬 Nature:

  • Type: Hypertonic glucose solution
  • Concentration: 25% w/v (25 grams of glucose in 100 mL of water)
  • pH Range: 3.5 to 6.5
  • Appearance: Clear, colorless or pale-yellow sterile solution
  • Osmolarity: High; must be given with care to avoid vein damage

🌟 Advantages:

  • Rapid correction of blood glucose in emergencies
  • Immediate energy source for critically ill or fasting patients
  • Can be combined with electrolytes or other nutrients
  • Compatible with parenteral nutrition regimens

📦 Common Packaging:

  • Ampoules or vials (25 mL, 50 mL, 100 mL)
  • Glass or plastic bottles (up to 500 mL for infusion use)
  • Each container labeled with concentration, batch no., expiry, and storage instructions

🧊 Storage:

  • Store at room temperature (15°C to 25°C)
  • Protect from light and freezing
  • Use only if the solution is clear and free from particles
  • Discard unused portion

⚠️ Precautions:

  • Monitor blood glucose before and during infusion
  • Use with caution in:
    • Diabetic patients
    • Renal impairment
    • Thiamine deficiency (risk of Wernicke’s encephalopathy)
  • Risk of:
    • Hyperglycemia
    • Electrolyte imbalance (especially hypokalemia)
    • Phlebitis at injection site
    • Fluid overload in cardiac or renal patients
  • Contraindications:
    • Hyperglycemia
    • Intracranial or intraspinal hemorrhage (glucose may worsen cerebral edema)

👩‍⚕️ Patient Advice:

  • For hospital or emergency setting only—not for self-use
  • Inform healthcare provider of:
    • Diabetes history
    • Cardiac, renal, or hepatic conditions
  • If prone to low blood sugar, carry oral glucose or sugar source
  • Watch for signs of:
    • Irritation or swelling at injection site
    • Sudden thirst or frequent urination (possible hyperglycemia)
  • Do not use at home unless instructed and trained by a medical professional

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