Insulin (Soluble)Injection 40 IU/mL

🔹 Insulin (Soluble) Injection 40 IU/mL – As Licensed


📄 **Description:

Soluble insulin**, also known as regular insulin, is a short-acting human insulin preparation used to control blood sugar levels in individuals with diabetes mellitus. It is administered subcutaneously or intravenously and begins acting within 30 minutes.


💊 Prescription / Use:

  • Indications:
    • Type 1 Diabetes Mellitus (insulin-dependent)
    • Type 2 Diabetes Mellitus when oral drugs are insufficient
    • Gestational diabetes
    • Diabetic ketoacidosis (IV use)
    • Perioperative glycemic control
  • Strength/Dosage Form:
    • Injection: 40 IU/mL (also available in 100 IU/mL)
    • Usually in 10 mL vials (400 IU total per vial)
  • Route of Administration:
    • Subcutaneous (SC): Preferred for routine use
    • Intravenous (IV): In emergencies like DKA
    • Intramuscular (rarely used)
  • Prescription Drug: Schedule H

🔬 Nature:

  • Short-acting recombinant human insulin
  • Onset: 30 minutes
  • Peak: 2–4 hours
  • Duration: 6–8 hours
  • Clear solution unlike cloudy intermediate/long-acting insulins

🌟 Advantages:

  • Reliable glycemic control in acute situations
  • Suitable for emergency use (IV route)
  • Can be mixed with intermediate/long-acting insulins
  • Compatible with sliding scale insulin therapy
  • Cost-effective and widely available

📦 Common Packaging:

  • 10 mL glass vial (with rubber stopper and aluminum seal)
  • Labeled with:
    • Insulin type (Soluble Human Insulin)
    • Concentration (40 IU/mL)
    • Batch number, Mfg/Exp dates, storage conditions
    • Color-coded cap (usually red or orange for regular insulin)

🧊 Storage:

  • Store between 2°C – 8°C (refrigerator)
  • Do not freeze
  • After opening: can be kept at room temperature (up to 25°C) for 28 days
  • Protect from direct sunlight and heat

⚠️ Precautions:

  • Monitor blood glucose levels frequently
  • Adjust dose during illness, surgery, or stress
  • Rotate injection sites to avoid lipodystrophy
  • Watch for hypoglycemia (most common adverse effect)
  • Do not share needles or vials
  • In IV use: dilute appropriately and monitor potassium levels

👩‍⚕️ Patient Advice:

  • Inject 30 minutes before meals
  • Learn proper injection technique (usually on thigh, abdomen, or upper arm)
  • Always carry sugar/candy in case of hypoglycemia:
    • Signs: shakiness, sweating, dizziness, confusion
  • Maintain a daily blood sugar log
  • Never skip meals after injecting insulin
  • Dispose of syringes/needles safely (in sharps container)
  • Store insulin properly — do not use if solution becomes cloudy or discolored

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