Calcium Gluconate Injection 100 mg/mL
🔹 Generic Name:
Calcium Gluconate
🔹 Strength & Formulation:
- 100 mg/mL
- Typically supplied in 10 mL vials or ampoules (i.e., 1 gram per 10 mL)
📌 Description:
Calcium gluconate is a calcium salt used to treat or prevent calcium deficiency. It is less irritating than calcium chloride and is commonly used in emergencies like hypocalcemia and hyperkalemia.
✅ Indications / Uses:
| Indication | Purpose |
|---|---|
| Hypocalcemia (low calcium) | Restores normal serum calcium levels |
| Hyperkalemia | Stabilizes cardiac membrane potential |
| Hypermagnesemia | Reverses magnesium toxicity |
| Calcium channel blocker overdose | Counteracts drug effects |
| Cardiac resuscitation (as needed) | In some ACLS protocols |
💊 Dosage & Administration:
Route: IV only
Form: 10% calcium gluconate = 100 mg/mL (i.e., 1 gram = 10 mL)
| Use Case | Adult Dose |
|---|---|
| Hypocalcemia | 1–2 grams IV slowly over 10–20 min |
| Hyperkalemia (with ECG changes) | 10 mL IV of 10% solution over 2–5 min |
| Calcium channel blocker overdose | 3–6 grams IV (may repeat if needed) |
IV Push only with extreme care and ECG monitoring. Avoid extravasation (can cause tissue necrosis).
✅ Advantages:
- Immediate correction of acute calcium deficiency
- Stabilizes myocardium in hyperkalemia
- Less irritant than calcium chloride
- Safer for peripheral IV administration
⚠️ Precautions & Warnings:
| Risk Factor | Precaution |
|---|---|
| Extravasation | Causes severe tissue damage |
| Digitalis therapy | Risk of arrhythmias—avoid rapid IV push |
| Renal impairment | Risk of hypercalcemia |
| Neonates | Caution due to immature renal clearance |
| Alkalosis | Can reduce ionized calcium effect |
🧴 Storage:
- Store below 25°C (77°F)
- Protect from light and freezing
- Use only clear, particulate-free solution