Here is a detailed overview of Methylergometrine Tablet 0.125 mg in leaflet-style format, without brand names, and suitable for patient or hospital use:
💊 Methylergometrine Tablet 0.125 mg
✅ DESCRIPTION
Methylergometrine (also known as methylergonovine) is a semi-synthetic ergot alkaloid used to prevent and treat postpartum hemorrhage (PPH) by promoting uterine contraction. It is effective in reducing blood loss after childbirth and during uterine involution.
🧪 FORMULATION
- Active Ingredient: Methylergometrine maleate 0.125 mg
- Dosage Form: Oral tablet
- Color/Shape: Usually white, small round tablet
- Route of Administration: Oral
🌿 NATURE
- Type: Uterotonic agent
- Pharmacological Class: Ergot derivative
- Mechanism of Action:
Acts directly on uterine smooth muscle, especially the upper segment → causes strong, sustained uterine contractions → reduces uterine bleeding
💊 USES
- Primary Uses:
- Prevention and treatment of postpartum hemorrhage
- Enhance uterine involution after delivery
- Support in management of subinvolution of the uterus
- Occasionally used in:
- Post-abortion bleeding (under supervision)
🌟 ADVANTAGES
- Rapid onset of action when taken orally
- Reduces need for injectable uterotonics in mild cases
- Convenient for post-discharge use to ensure uterine tone
- Improves uterine involution, reducing lochia duration
⚠️ PRECAUTIONS
Do Not Use in:
- Hypertension or preeclampsia/eclampsia
- Heart disease
- Hepatic or renal impairment
- Hypersensitivity to ergot alkaloids
Common Side Effects:
- Nausea, vomiting
- Headache
- Increased blood pressure
- Chest pain or palpitations (rare)
Serious Risks (rare):
- Hypertensive crisis
- Vasospasm (e.g., in coronary or cerebral vessels)
Precautions in Use:
- Monitor blood pressure before and during use
- Avoid in breastfeeding within the first 12 hours after dose, unless advised
- Do not exceed prescribed dosage
📅 DOSAGE (Typical Adult)
- 0.125 mg orally 3 to 4 times daily for up to 1 week
(Always follow doctor’s instructions)
🧊 STORAGE
- Store at below 25°C (room temperature)
- Protect from light and moisture
- Keep in original packaging
- Keep out of reach of children
- Do not use after expiry