💊 Paracetamol Suppository 170 mg
📘 **Description:
Paracetamol (also known as acetaminophen)** suppository 170 mg is a rectal formulation used to manage fever and mild to moderate pain in children, especially when oral administration is not possible (due to vomiting, unconsciousness, or refusal to swallow). It offers systemic effects through rectal absorption.
🔬 Nature / Mechanism of Action:
Paracetamol acts as:
- An antipyretic (fever-reducing)
- An analgesic (pain-relieving)
It works by inhibiting prostaglandin synthesis in the central nervous system and has minimal anti-inflammatory action.
🩺 Prescription / Uses:
| Indication | Use |
|---|---|
| Fever | Especially in children who can’t take oral meds |
| Mild to moderate pain | Headache, post-immunization discomfort, sore throat |
| Teething pain | Pediatric dental discomfort |
| Post-surgical or trauma-related | Pediatric pain relief after minor procedures |
| Nausea/Vomiting | Alternative to oral dosing |
✅ Advantages:
- Useful in vomiting/unconscious children
- Bypasses gastric absorption, ideal for GI-sensitive patients
- Less frequent dosing due to prolonged absorption
- Good for night-time dosing
⚠️ Precautions:
- Dose should be based on child’s weight and age
- Avoid in children with:
- Severe liver disease
- Rectal bleeding or irritation
- Avoid duplicate dosing (e.g., combining with paracetamol syrup or tablets)
- Consult pediatrician before prolonged use
📏 Typical Pediatric Dosage Guidelines:
| Body Weight | Typical Rectal Dose |
|---|---|
| 15–22 kg | 170 mg every 6 hours as needed |
| Max daily dose | 60 mg/kg/day in divided doses |
⚠️ Always follow healthcare provider’s advice. Do not exceed the recommended total daily dose.
📦 Storage:
- Store below 25°C, preferably in a refrigerator
- Protect from heat – may melt
- Keep out of reach of children