Latanoprost Drops 0.005 %

Here is a detailed product overview of Latanoprost Eye Drops 0.005%:


DESCRIPTION

Latanoprost 0.005% Ophthalmic Solution is a prostaglandin F2α analogue used to reduce intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It works by increasing the outflow of aqueous humor from the eye.


🧪 FORMULATION

  • Active Ingredient: Latanoprost 0.005% (50 mcg/mL)
  • Preservative: Benzalkonium chloride 0.02%
  • Other Excipients:
    • Sodium chloride
    • Sodium phosphate (monobasic and dibasic)
    • Water for injection
    • pH adjusted with sodium hydroxide or hydrochloric acid
  • Form: Sterile ophthalmic solution (eye drops)

🌿 NATURE

  • Type: Synthetic prostaglandin analogue
  • Action: Increases uveoscleral outflow of aqueous humor → lowers intraocular pressure
  • Onset of Action: 3–4 hours
  • Peak Effect: 8–12 hours
  • Duration: Up to 24 hours

💊 USES

  1. Primary Use:
    • Open-angle glaucoma
    • Ocular hypertension
  2. Off-label uses (under doctor supervision):
    • Normal-tension glaucoma
    • Pediatric glaucoma (in select cases)

🌟 ADVANTAGES

  • Once-daily dosing (typically at night)
  • Highly effective IOP reduction (25–35%)
  • Minimal systemic absorption
  • Fewer systemic side effects compared to beta-blocker eye drops
  • Can be combined with other IOP-lowering medications

⚠️ PRECAUTIONS

  • Local side effects:
    • Eye redness (hyperemia)
    • Iris color darkening (permanent)
    • Eyelash growth or thickening
    • Eyelid skin pigmentation
    • Blurred vision, irritation
  • Cautions in:
    • Aphakia or pseudophakia (risk of macular edema)
    • History of herpetic keratitis
    • Pregnancy & breastfeeding (consult physician)
    • Contact lens wearers: remove lenses before instillation and wait 15 minutes before reinserting
  • Avoid contamination: Do not touch dropper tip to any surface or eye.

🧊 STORAGE

  • Before opening:
    • Store at 2°C to 8°C (refrigerated)
    • Protect from light and moisture
  • After opening:
    • Can be stored at room temperature (up to 25°C) for up to 6 weeks
    • Keep the bottle tightly closed
    • Discard unused contents after 6 weeks from first use

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